IBDase
Mucosal protease and their inhibitors in inflammatory bowel disease: From etiopathogenetic insight to innovative therapy
Scientific publications 2010
- F.A. Carvalho, N. Barnich, A. Sivignon, C. Darcha, C.H.F. Chan, C.P. Stanners and A. Darfeuille-Michaud (2009) Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM. The Journal of Experimental Medicine 206 (10): 2179-2189.
download pdf
- P. Lapaquette, A.-L.Glasser, A. Huett, R. J. Xavier and A. Darfeuille-Michaud (2010) Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cellular Microbiology 12(1): 99-113. download pdf
- S. Miquel, L. Claret, R. Bonnet, I. Dorboz, N. Barnich and A. Darfeuille-Michaud (in press) Role of decreased levels of Fis histone-like protein in Crohn's disease-associated AIEC LF82 bacteria interacting with intestinal epithelial cells. Journal of Bacteriology. e-publication ahead of print. Pubmed
Scientific publications 2009
- M.E. Johansson, K.A. Thomsson and G.C. Hansson (2009) Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. Journal of Proteome Research 8(7): 3549-3557. Pubmed
- S. Banerjee, B. Oneda, L. M. Yap, D. Jewell, G. Matters, L. Fitzpatrick, F. Seibold, E. Sterchi, T. Ahmad, D. Lottaz and J. Bond (2009) MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal Immunology 2: 220-231. download pdf
Note: Research leading to the above publication had been conducted mainly before the onset of the IBDase project.
- F.A. Carvalho, N. Barnich, A. Sivignon, C. Darcha, C.H.F. Chan, C.P. Stanners and A. Darfeuille-Michaud (2009) Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM. The Journal of Experimental Medicine 206 (10): 2179-2189.
download pdf
- P. Lapaquette, A.-L.Glasser, A. Huett, R. J. Xavier and A. Darfeuille-Michaud (2010) Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cellular Microbiology 12(1): 99-113. download pdf
- S. Miquel, L. Claret, R. Bonnet, I. Dorboz, N. Barnich and A. Darfeuille-Michaud (in press) Role of decreased levels of Fis histone-like protein in Crohn's disease-associated AIEC LF82 bacteria interacting with intestinal epithelial cells. Journal of Bacteriology. e-publication ahead of print. Pubmed
Scientific publications 2009
- M.E. Johansson, K.A. Thomsson and G.C. Hansson (2009) Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. Journal of Proteome Research 8(7): 3549-3557. Pubmed
- S. Banerjee, B. Oneda, L. M. Yap, D. Jewell, G. Matters, L. Fitzpatrick, F. Seibold, E. Sterchi, T. Ahmad, D. Lottaz and J. Bond (2009) MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal Immunology 2: 220-231. download pdf
Note: Research leading to the above publication had been conducted mainly before the onset of the IBDase project.
Flyer
The project has produced a brochure to raise awareness of IBDase among clinicians, patients, and the interested public. If you are interested to receive copies, also for further dissemination, please contact the project office (follow the link at the base of the page). download flyer
The project has produced a brochure to raise awareness of IBDase among clinicians, patients, and the interested public. If you are interested to receive copies, also for further dissemination, please contact the project office (follow the link at the base of the page). download flyer